According to the American Cancer Society, approximately 102,480 people are diagnosed with colorectal cancer every year, making it one of the most common forms of this disease. Age, genetic background and various syndromes can increase an individual's likelihood of developing this ailment. However, thanks to advancements in diagnosis and treatment, remission and recovery rates are on the rise.
One natural compound that could come to play a role in more effective colorectal cancer treatment is curcumin – the bioactive ingredient in turmeric that is known for its antioxidant and anti-inflammatory properties, among other beneficial traits. We've documented past research on this topic, including the compound's potential to restrict the growth of prostate cancer. Now, scientists from National Taiwan University in Taipei have shed further light on how curcumin may curb the development of colorectal cancer in various ways.
"We explored the underlying molecular mechanisms of curcumin on metastasis of [colorectal cancer] cells in vitro and in vivo," the researchers stated in a study abstract on PubMed. "Curcumin significantly inhibits cell migration, invasion, and colony formation in vitro and reduces tumor growth and liver metastasis in vivo."
Metastasis is the process by which cancer cells spread from one part of the body to another, and various studies have indicated that curcumin could block this process – which is a particularly promising function for aggressive forms of cancer. Further research is necessary to solidify this link, but curcumin seems poised to become a supplementary treatment in many clinical settings.
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